Although we wrote this post together, we have chosen to present the following through Nikki’s eyes.
Nikki's Story: Journey through Zoloft
During my winter break from college in December 2010, I was prescribed Zoloft—another addition to the growing list of medications I was already taking.
My treatment before Zoloft included three psychiatric drugs. Yet my depression, general mood, and overall wellness continued to deteriorate.
It was decided by my healthcare provider at this time to replace one of my existing Selective Serotonin Reuptake Inhibitors (SSRIs) with Zoloft, indicating it might offer better results.
I trusted her judgment and followed her guidance never fully understanding the potential effects of switching medications even in the same class.
I was initially prescribed Zoloft for just two months, but even in that short time, the effects were profound.
I felt persistently unwell—physically shaky, emotionally dulled, and weighed down by a deepening depression. It’s hard to recall much from that period; and honestly, most of what I know comes from the notes my mom kept in my prescription drug journal.
Although my memory from the time I was on Zoloft is clouded, the painful withdrawal is all too clear in my mind.
It was difficult to grasp how a medication I’d taken for such a brief period—and never at the clinical dose—could trigger such intense withdrawal symptoms. But it did.
And even now, I can still vividly remember the waves of lightheadedness, nausea, and the excruciating unwellness.
Because the withdrawal was so intense, my healthcare provider recommended restarting Zoloft to taper off more gradually. I agreed, and that decision kept me on the medication for another four months.
Unfortunately, the symptoms didn’t ease. Throughout the whole tapering off period and afterward, I continued having lightheadedness, nausea, and overall sickness, leaving me in a state of constant physical discomfort and mental confusion.
With my mom questioning my treatment plan with my healthcare provider, my counselor made it clear—she no longer wanted my mom present during our sessions.
Not only that, but she also began refusing to communicate with mom about my prescription drug plan altogether even though I gave consent for my mom to do so. At the time, she framed it as a move towards my adulthood and taking charge of my own health wellness. Being in a confused state, I believed what she was telling me.
But looking back now, I recognize that this was a red flag.
Learning from my journey on Zoloft.
Looking back, one of the hardest parts of being on Zoloft wasn’t just the medication itself—it was how disconnected I felt from my own care. I couldn’t fully grasp or question what my healthcare provider was telling me. I didn’t have the clarity to advocate for myself, and that left me vulnerable.
What I needed was a healthcare advocate. Unfortunately, instead of my healthcare provider encouraging my mom’s support, she dismissed it.
First, why an advocate is important
An advocate is someone who shows up for you when you can’t show up for yourself. They might be a parent, a partner, a trusted friend—anyone who genuinely cares about your well-being. This person helps interpret medical advice, asks thoughtful questions, and works with you to explore the best treatment options. Most importantly, they protect your interests when you’re not in a place to do so yourself.
Why Advocacy Matters
There may be times when your mind feels foggy, overwhelmed, or simply unable to process what’s being said. That’s not a failure—it’s a signal that you need support. And while we hope every healthcare provider offers clear, compassionate guidance, the truth is: not all do. That’s why having someone in your corner matters so much.
I have learned that when transparency and collaboration are replaced with secrecy and exclusion, especially in matters as serious as medication, it’s often a sign that something is off.
Second, why it is crucial to be knowledgeable about your prescribed medication
During my time on SSRIs, I learned—often the hard way—how important it is to be informed about the medications that we are prescribed. At the time, I didn’t know how to properly taper off a drug, and I wasn’t aware that switching from one SSRI to another could trigger withdrawal symptoms. I was told to stop Lexapro abruptly and begin Zoloft the very next day.
My counselor made the switch without warning me about the potential consequences of discontinuing Lexapro, which I had been taking for seven months. Lexapro, like many SSRIs, should never be stopped suddenly. Also, the transition to Zoloft was made without considering how it might interact with other medications I was already taking.
I was advised to cut Zoloft tablets in half, and over the next two months, my dosage was repeatedly adjusted—up and down—without a clear plan. As my symptoms worsened, I was told to stop Zoloft abruptly. Again, no tapering. No discussion. Just another sudden shift. And then, without pause, a new medication was prescribed in its place.
This experience taught me that understanding your medication isn’t just helpful—it’s essential.
You have the right to ask questions, to understand the risks, and to be part of the decision-making process. Because when you’re not informed, your body ends up bearing the consequences.
Note: All information in “Nikki’s Story and Mom’s Story” are based on detail journals covering seven years of Nikki’s life on prescription drugs.
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